Selected Publications and Presentations

Modified

February 1, 2025

A list of select publications and presentations that I supported in my work at SCRI and Fred Hutch. I am first author of a research journal article on CBFA2T3-GLIS pediatric AML (pAML) patients and co-first author for a research article on NUP98-rearranged pAML.

I assisted with a large part of the data analysis/processing, figure generation, and manuscript writing on these publications.

The Data Viz section is an overview some of the figures generated for publications I supported.

  • Zanghí, G.*, Patel, H.*, Smith, J.L.*, .. Vaughan, A. M. and Kappe, S. H. I.. Genome-wide gene expression profiles throughout human malaria parasite liver stage development in humanized mice. Nature Microbiology. 2025. DOI:https://doi.org/10.1038/s41564-024-01905-5

  • Bertrums, E. J. M.*,Smith, J. L.* , Harmon, L.*, … Meshinchi, S. Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia. Haematologica. 2023. DOI:10.3324/haematol.2022.281653

  • Farrar, J. E., Smith, J. L., … Meshinchi, S. Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. Journal of Clinical Oncology. 2023. DOI:10.1200/jco.22.01114

  • Chisholm, K. M., Smith, J., Heerema-McKenney, A. E., … Meshinchi, S., & Kahwash, S. B. Pathologic, cytogenetic, and molecular features of acute myeloid leukemia with megakaryocytic differentiation: A report from the Children’s Oncology Group. Pediatric blood & cancer. 2023 DOI:10.1002/pbc.30251

  • Huang, B.J., Smith, J.L., Farrar, J.E. … Meshinchi, S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nature Communications. 2022. DOI:10.1038/s41467-022-33244-6

  • Le, Q., Hadland, B., Smith, J. L., … Meshinchi, S. CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target. Journal of Clinical Investigation. 2022. DOI:10.1172/jci157101

  • Huang, B., Smith, J. L., Wang, J., … Meshinchi, S. CBFB-MYH11 Fusion Transcripts Distinguish Acute Myeloid Leukemias with Distinct Molecular Landscapes and Outcomes. Blood Advances 2021. DOI:10.1182/bloodadvances.2021004965

  • Chisholm, K., Heerema-McKenney, A., Choi, J., Smith, J.L. … Kahwash, B. Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children’s Oncology Group. Blood Advances 2020. DOI:10.1182/bloodadvances.2020002712

  • Noort, S., Wander, P., Alonzo, T. A., Smith, J.L., … Meshinchi, S. The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia. Haematologica 2020. DOI:10.3324/haematol.2019.236745

  • Smith, J. L., Ries, R. E., Hylkema, T., Alonzo, T. A, … Meshinchi, S. Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-positive AML Defines Novel Therapeutic Options – A COG and TARGET Pediatric AML Study. Clinical Cancer Research 2019. DOI:10.1158/1078-0432.CCR-19-1800

  • Noort, S., Zimmermann, M., Reinhardt, D., Cuccuini, W., Pigazzi, M., Smith, J., … Zwaan, C. M. Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group. Blood 2018. DOI:10.1182/blood-2018-05-849059

* Indicates co-first authorship

Additional Publications

  • IGNITE, panelist on careers in data science and technology to promote gender equity and representation in STEM. IGNITE Field Trip with Rainier Beach High School (Seattle Children’s Research Institute, 2024). link

  • Molecular Medicine Tri-conference, panelist on AI in Genomics and Precision Medicine (San Francisco, CA, 2020). link.

  • American Society for Hematology, poster on Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia - a COG and Tpaml Study (Orlando, FL, 2019). DOI.

  • Brotman Baty Pediatric Sequencing Symposium, oral presentation on Long Non-coding RNAs Associate with Outcome in Pediatric Acute Myeloid Leukemia (Seattle, WA, 2019).

  • American Society for Hematology, oral presentation on Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options — a COG and Target Pediatric AML Study (San Diego, CA, 2018). DOI.

  • American Society for Hematology, oral presentation on The LSC17 Leukemic Stem Cell Signature Predicts Outcome in Pediatric Acute Myeloid Leukemia. Abstract Achievement Award Recipient (Atlanta, GA, 2017). link

Other Presentations

  • American Society for Hematology, poster on ETS Family Transcription Factor Fusions in Childhood AML: Distinct Expression Networks and Clinical Implications (Virtual, 2021). DOI.

  • American Society for Hematology, poster on The Transcriptomic Landscape of NUP98-Rearranged Pediatric Acute Myeloid Leukemia (Virtual, 2020).DOI.